Why Combine Myo-Inositol and D-Chiro Inositol in a 40:1 Formula?

July 12, 2026

If you have looked at inositol supplements, you have seen the number 40:1. It is not marketing, it reflects the natural balance of myo-inositol to D-chiro-inositol found in the body, and it is the ratio Nutrovell built its formula around. Here is why combining the two forms in this ratio makes sense.

Two partners, not rivals

Myo-inositol and D-chiro-inositol are stereoisomers, closely related molecules that play complementary roles in insulin signalling and ovarian function. The body naturally converts some myo-inositol into D-chiro, so they work as a team rather than competitors.

Why the 40:1 ratio

Roughly 40 parts myo-inositol to 1 part D-chiro-inositol mirrors the balance found in healthy plasma, and it is the ratio most used in the research literature. Nutrovell provides exactly that, 2,000 mg of myo-inositol to 50 mg of D-chiro-inositol, so you get a physiologically sensible, research-informed combination.

Why not myo-inositol alone

Providing both forms means you deliver D-chiro-inositol directly rather than relying entirely on your body's conversion. Combining them in the balanced 40:1 ratio is designed to support the complementary signalling roles of each.

The supporting nutrients

The formula also includes active L-methylfolate and vitamin D3, both especially relevant to women's reproductive and preconception wellness. Folate supports healthy cell division, and vitamin D3 supports normal hormonal and cellular function.

How to take it

Take four capsules daily with food. If you are trying to conceive, undergoing fertility treatment, pregnant, or on diabetes medication, use it under your doctor's guidance and account for folate and vitamin D from any prenatal.

The bottom line

Myo-inositol and D-chiro-inositol are combined in a 40:1 ratio because that mirrors the body's natural balance and reflects the research. Nutrovell Myo-Inositol & D-Chiro Inositol Complex delivers that balanced ratio with active folate and vitamin D3 for well-rounded reproductive support.